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Alofanib (RPT835)

CAT: 1568-C13642-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C13642-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1612888-66-0
Target
FGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=CC (=C (C=C1C2=CN=CC=C2) NS (=O) (=O) C3=CC=CC (=C3) C (=O) O) [N+] (=O) [O-]
Molecular Formula
C19H15N3O6S
Additionnal Information
Alofanib (RPT835) is a novel selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect with IC50 <10 nM on FGF2-induced phoshphorylation of FRS2a in KATO III cells. It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding.
Storage Conditions
3 years -20°C powder

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