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Z-IETD-FMK

CAT: 1568-C12597-10mM/1mLSize: 10 mm/ 1 mLDry Ice: YesHazardous: No
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CAT#:1568-C12597-10mM/1mLSize:10 mm/ 1 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
210344-98-2
Synonyms
Caspase-8 Inhibitor, Z-IE (OMe) TD (OMe) -FMK
Target
Caspase
Applications
Apoptosis
Smiles
CCC (C) C (C (=O) NC (CCC (=O) OC) C (=O) NC (C (C) O) C (=O) NC (CC (=O) OC) C (=O) CF) NC (=O) OCC1=CC=CC=C1
Molecular Formula
C30H43FN4O11
Additionnal Information
Z-IETD-FMK (Caspase-8 Inhibitor, Z-IE (OMe) TD (OMe) -FMK) is a specific Caspase-8 inhibitor. Z-IETD-FMK is also an inhibitor of granzyme B.
Storage Conditions
2 years -80 in solvent

Chemical Information

Z-IETD-fmk
CAS Number210344-98-2
PubChem CID25108681
IUPAC Namemethyl (4S)-5-[[(2S,3R)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-[[(2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-oxopentanoate
Molecular FormulaC30H43FN4O11
Molecular Weight654.7
XLogP1.2
Topological Polar Surface Area216
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count12
Rotatable Bond Count22
Heavy Atom Count46
Formal Charge0
Complexity1050
SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1
InChI
InChI=1S/C30H43FN4O11/c1-6-17(2)25(35-30(43)46-16-19-10-8-7-9-11-19)28(41)32-20(12-13-23(38)44-4)27(40)34-26(18(3)36)29(42)33-21(22(37)15-31)14-24(39)45-5/h7-11,17-18,20-21,25-26,36H,6,12-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,40)(H,35,43)/t17-,18+,20-,21-,25-,26-/m0/s1
InChIKey
PHLCQASLWHYEMX-DEKIMQJDSA-N
Chemical Structure
2D Structure
2D structure of Z-IETD-fmk
CAS: 210344-98-2
CID: 25108681
Formula: C30H43FN4O11
MW: 654.7
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight654.7
XLogP31.2
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count12
Rotatable Bond Count22
Exact Mass654.29123636
Monoisotopic Mass654.29123636
Topological Polar Surface Area216 Ų
Heavy Atom Count46
Formal Charge0
Complexity1050
Isotope Atom Count0
Defined Atom Stereocenter Count6
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
B3232-.1Z-IETD-FMK
A12800-10Z-IETD-FMK 10mg
A12800-2Z-IETD-FMK 2mg
A12800-25Z-IETD-FMK 25mg
HY-101297RZ-IETD-FMK (Standard)
A12800-5Z-IETD-FMK 5mg
A12800-1Z-IETD-FMK 1mg

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