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MD-224

CAT: 1568-C12303-25mgSize: 25 mgDry Ice: NoHazardous: No
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CAT#:1568-C12303-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2136247-12-4
Target
MDM2/MDMX
Applications
Apoptosis
Molecular Formula
C48H43Cl2FN6O6
Additionnal Information
MD-224 is a highly potent and effective degrader of the Human murine double minute 2 (MDM2) protein, the main cellular inhibitor of the tumor suppressor p53. It strongly inhibits cell growth in leukemia cell lines with wild-type p53 and induces complete and lasting tumor regression in the RS4;11 xenograft tumor model.