Products for Research Use Only
RegisterLogin

TAK-901

CAT: 1568-C17022-50mgSize: 50 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:1568-C17022-50mgSize:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
934541-31-8
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
CCS (=O) (=O) C1=CC=CC (=C1) C2=CC (=C (C3=C2C4=C (N3) N=CC (=C4) C) C) C (=O) NC5CCN (CC5) C
Molecular Formula
C28H32N4O3S
Additionnal Information
TAK-901 is a novel inhibitor of Aurora A/B with IC50 of 21 nM/15 nM. It is not a potent inhibitor of cellular JAK2, c-Src or Abl. Phase 1.
Storage Conditions
2 years -80 in solvent

Chemical Information

Tak-901

TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others.

CAS Number934541-31-8
PubChem CID16124208
IUPAC Name5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methylpiperidin-4-yl)-9H-pyrido[2,3-b]indole-7-carboxamide
Molecular FormulaC28H32N4O3S
Molecular Weight504.6
XLogP4.5
Topological Polar Surface Area104
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count36
Formal Charge0
Complexity884
SMILES
CCS(=O)(=O)C1=CC=CC(=C1)C2=CC(=C(C3=C2C4=C(N3)N=CC(=C4)C)C)C(=O)NC5CCN(CC5)C
InChI
InChI=1S/C28H32N4O3S/c1-5-36(34,35)21-8-6-7-19(14-21)23-15-22(28(33)30-20-9-11-32(4)12-10-20)18(3)26-25(23)24-13-17(2)16-29-27(24)31-26/h6-8,13-16,20H,5,9-12H2,1-4H3,(H,29,31)(H,30,33)
InChIKey
WKDACQVEJIVHMZ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Tak-901
CAS: 934541-31-8
CID: 16124208
Formula: C28H32N4O3S
MW: 504.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight504.6
XLogP34.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass504.21951207
Monoisotopic Mass504.21951207
Topological Polar Surface Area104 Ų
Heavy Atom Count36
Formal Charge0
Complexity884
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
C17153-50mgTAK-715
C17153-10mM/1mLTAK-715
C07646-5mgTAK-960
C16953-10mgTAK-733
C16953-01TAK-733
C17066-01TAK-285
C07646TAK-960
C08722-01TAK-733
C13432-5mgTAK-063
C13432-25mgTAK-063

Alternative Products

CatalogName
T2709-01TAK-901
FT27989TAK 901
A11067-25TAK-901 25mg
A11067-100TAK-901 100mg
A11067-10TAK-901 10mg

Popular Products