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GSK690693

CAT: 1568-C16120-200mgSize: 200 mgDry Ice: YesHazardous: No
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CAT#:1568-C16120-200mgSize:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
937174-76-0
Target
Akt
Applications
PI3K/Akt/mTOR
Smiles
CCN1C2=C (C (=NC=C2OCC3CCCNC3) C#CC (C) (C) O) N=C1C4=NON=C4N
Molecular Formula
C21H27N7O3
Additionnal Information
GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM in cell-free assays, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. GSK690693 also potently inhibits AMPK and DAPK3 from the CAMK family with IC50 of 50 nM and 81 nM, respectively. GSK690693 affects Unc-51-like autophagy activating kinase 1 (ULK1) activity, robustly inhibits STING-dependent IRF3 activation. Phase 1.
Storage Conditions
2 years -80 in solvent

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