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DC260126

CAT: 1568-C07290-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C07290-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
346692-04-4
Target
GPR
Applications
GPCR & G Protein
Smiles
CCCCC1=CC=C (C=C1) NS (=O) (=O) C2=CC=C (C=C2) F
Molecular Formula
C16H18FNO2S
Additionnal Information
DC260126, a small organic antagonist for GPR40 (FFAR1), dose-dependently inhibits GPR40-mediated Ca2+ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50=6.28, 5.96, 7.07, 4.58 μM, respectively), reduces GTP-loading and ERK1/2 phosphorylation stimulated by linoleic acid in GPR40-CHO cells, suppresses palmitic acid potentiated glucose-stimulated insulin secretion, and negatively regulates GPR40 mRNA expression induced by oleic acid in Min6 cells.
Storage Conditions
3 years -20°C powder

Chemical Information

N-(4-butylphenyl)-4-fluorobenzenesulfonamide
CAS Number346692-04-4
PubChem CID2843133
IUPAC NameN-(4-butylphenyl)-4-fluorobenzenesulfonamide
Molecular FormulaC16H18FNO2S
Molecular Weight307.4
XLogP4.4
Topological Polar Surface Area54.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Heavy Atom Count21
Formal Charge0
Complexity391
SMILES
CCCCC1=CC=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)F
InChI
InChI=1S/C16H18FNO2S/c1-2-3-4-13-5-9-15(10-6-13)18-21(19,20)16-11-7-14(17)8-12-16/h5-12,18H,2-4H2,1H3
InChIKey
CNGHPXKWPGIDSK-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(4-butylphenyl)-4-fluorobenzenesulfonamide
CAS: 346692-04-4
CID: 2843133
Formula: C16H18FNO2S
MW: 307.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight307.4
XLogP34.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass307.10422815
Monoisotopic Mass307.10422815
Topological Polar Surface Area54.6 Ų
Heavy Atom Count21
Formal Charge0
Complexity391
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BUP02286-01DC260126
A19630-10DC260126 10mg
A19630-5DC260126 5mg
A19630-50DC260126 50mg
A19630-100DC260126 100mg
A19630-25DC260126 25mg
TBI1531-5MGDC260126, GPR40 antagonist
A19630-10mM-DDC260126 10mM * 1mL in DMSO

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