BI-671800

CAT: 1568-C07211-5mgSize: 5 mgDry Ice: NoHazardous: No

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CAT#:1568-C07211-5mgSize:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1093108-50-9

Synonyms

AP-761, Cmpd A

Target

Prostaglandin Receptor

Applications

GPCR & G Protein

Smiles

CN (C) C1=C (C (=NC (=N1) CC2=CC=C (C=C2) NC (=O) C3=CC=C (C=C3) C (F) (F) F) N (C) C) CC (=O) O

Molecular Formula

C25H26F3N5O3

Additionnal Information

BI-671800 (AP-761, Cmpd A) is a highly specific and potent antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2) with IC50 of 4.5 nM and 3.7 nM for PGD2 binding to human CRTH2 and murine CRTH2, respectively. BI-671800 is associated with a small improvement in FEV1 in symptomatic controller-naïve asthma patients, and in patients on ICS.

Storage Conditions

3 years -20°C powder

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BA5725-25	BI-671800
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A18902-10	BI-671800 10mg
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A18902-200	BI-671800 200mg
A18902-50	BI-671800 50mg
A18902-25	BI-671800 25mg
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BI-671800

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