Products for Research Use Only
RegisterLogin

Alpelisib hydrochloride

CAT: 1568-C04959-100mgSize: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1568-C04959-100mgSize:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1584128-91-5
Target
PI3K
Applications
PI3K/Akt/mTOR
Molecular Formula
C19H22F3N5O2S.ClH
Additionnal Information
Alpelisib hydrochloride is a potent and selective inhibitor of PI3Kα with an IC50 of 0.005 μM, 1.2 μM, 0.29 μM, 0.25 μM for p110α, p110β, p110δ, p110γ, respectively. It exhibits good efficacy in inhibiting the growth of PI3Ka driven tumors and can be used in cancer research.

Chemical Information

Alpelisib hydrochloride
CAS Number1584128-91-5
PubChem CID139035009
IUPAC Name(2S)-1-N-[4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)-4-pyridinyl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide;hydrochloride
Molecular FormulaC19H23ClF3N5O2S
Molecular Weight477.9
Topological Polar Surface Area129
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count4
Heavy Atom Count31
Formal Charge0
Complexity663
SMILES
CC1=C(SC(=N1)NC(=O)N2CCC[C@H]2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F.Cl
InChI
InChI=1S/C19H22F3N5O2S.ClH/c1-10-14(11-6-7-24-13(9-11)18(2,3)19(20,21)22)30-16(25-10)26-17(29)27-8-4-5-12(27)15(23)28;/h6-7,9,12H,4-5,8H2,1-3H3,(H2,23,28)(H,25,26,29);1H/t12-;/m0./s1
InChIKey
HJNPFZMOUFLFRE-YDALLXLXSA-N
Chemical Structure
2D Structure
2D structure of Alpelisib hydrochloride
CAS: 1584128-91-5
CID: 139035009
Formula: C19H23ClF3N5O2S
MW: 477.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight477.9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count4
Exact Mass477.1213083
Monoisotopic Mass477.1213083
Topological Polar Surface Area129 Ų
Heavy Atom Count31
Formal Charge0
Complexity663
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
C08881-10mM/1mLAlpelisib (BYL719)
C08881-01Alpelisib (BYL719)
C08881-5mgAlpelisib (BYL719)
C08881-10mgAlpelisib (BYL719)
C08881-100mgAlpelisib (BYL719)
C08881-1gAlpelisib (BYL719)
C17209-10mM/1mLOxybutynin hydrochloride
C09533-25mgMafenide hydrochloride
C09534-1gNortriptyline hydrochloride
C09537-25mgBenactyzine hydrochloride

Alternative Products

CatalogName
HY-15244A-01Alpelisib (hydrochloride)
E8308-5mgAlpelisib hydrochloride
A21794-100Alpelisib hydrochloride 100mg
A21794-10Alpelisib hydrochloride 10mg
A21794-1Alpelisib hydrochloride 1mg
A21794-5Alpelisib hydrochloride 5mg
A21794-50Alpelisib hydrochloride 50mg
A21794-25Alpelisib hydrochloride 25mg
HY-15244-01Alpelisib

Popular Products