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SB 202190 hydrochloride

CAT: 1568-C03564-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C03564-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
350228-36-3
Target
P38 MAPK
Applications
MAPK
Molecular Formula
C20H14FN3O.ClH
Additionnal Information
SB 202190 hydrochloride is a selective inhibitor of p38 MAP kinase with IC50 values of 50 nM for p38α and 100 nM for p38β2. It exhibits anti-cancer activity, induces autophagy, and is studied for its role in hippocampus-dependent spatial memory and apoptotic regulation under chronic ischemia.

Chemical Information

SB 202190 Hydrochloride
CAS Number350228-36-3
PubChem CID135451580
IUPAC Name4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenol;hydrochloride
Molecular FormulaC20H15ClFN3O
Molecular Weight367.8
Topological Polar Surface Area61.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count26
Formal Charge0
Complexity415
SMILES
C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)O.Cl
InChI
InChI=1S/C20H14FN3O.ClH/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15;/h1-12,25H,(H,23,24);1H
InChIKey
XOQSUTIMRLPFPB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of SB 202190 Hydrochloride
CAS: 350228-36-3
CID: 135451580
Formula: C20H15ClFN3O
MW: 367.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight367.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass367.0887680
Monoisotopic Mass367.0887680
Topological Polar Surface Area61.8 Ų
Heavy Atom Count26
Formal Charge0
Complexity415
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
E5786-01SB 202190 hydrochloride
574871SB-202190 hydrochloride
HY-10295A-01SB 202190 (hydrochloride)
HY-10295AR-01SB 202190 (hydrochloride) (Standard)
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