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LYMTAC-2

CAT: 1568-C03319-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:1568-C03319-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Additionnal Information
LYMTAC-2 is a lysosomal-targeting chimera (LYMTAC) designed to degrade membrane-associated proteins by leveraging lysosomal membrane proteins (LMPs) like RNF152, LAPTM4a, and LAPTM5. It forms a ternary complex with its target protein, such as KRASG12D, and facilitates relocalization to the lysosome, leading to ubiquitin-dependent degradation. It has the potential to study membrane protein regulation and develop strategies to overcome resistance in KRAS-driven signaling pathways.

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