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BHPI

CAT: 1568-C03235-100mgSize: 100 mgDry Ice: NoHazardous: No
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CAT#:1568-C03235-100mgSize:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
56632-39-4
Target
Estrogen/progestogen Receptor
Applications
Endocrinology & Hormones
Molecular Formula
C21H17NO3
Additionnal Information
BHPI is a potent noncompetitive inhibitor of estrogen receptor α (ERα), which disrupts the protective estrogen–ERα-mediated activation of the unfolded protein response (UPR), leading to sustained UPR activation. It specifically inhibits the growth of drug-resistant ERα-positive breast and ovarian cancer cells and induces significant tumor regression in a mouse xenograft model of breast cancer.

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