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Aniracetam (Standard)

CAT: 0804-HY-10932R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-10932R-01Size:10 mg
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Description
Aniracetam (Standard) is the analytical standard of Aniracetam. This product is intended for research and analytical applications. Aniracetam (Ro 13-5057) is an orally active neuroprotective agent, possessing nootropics effects. Aniracetam potentiates the ionotropic quisqualate (iQA) responses in the CA1 region of rat hippocampal slices. Aniracetam also potentiates the excitatory post synaptic potentials (EPSPs) in Schaffer collateral-commissural synapses. Aniracetam can prevents the CO2-induced impairment of acquisition in hypercapnia model rats. Aniracetam can be used to research cerebral dysfunctional disorders[1][2][3][4].
CAS Number
72432-10-1
Product Name Alternative
Ro 13-5057 (Standard)
UNSPSC
12352005
Target
IGluR; nAChR; Reference Standards
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aniracetam-standard.html
Smiles
O=C(N1CCCC1=O)C2=CC=C(OC)C=C2
Molecular Formula
C12H13NO3
Molecular Weight
219.24
References & Citations
[1]Nakamura K, et al. Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur J Pharmacol. 2001 May 18;420 (1) :33-43.|[2]Vaglenova J, et al. Aniracetam reversed learning and memory deficits following prenatal ethanol exposure by modulating functions of synaptic AMPA receptors. Neuropsychopharmacology. 2008 Apr;33 (5) :1071-83. Epub 2007 Jul 4.|[3]Ito I, et al. Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam. J Physiol. 1990 May;424:533-43.|[4]Cumin R, et al. Effects of the novel compound aniracetam (Ro 13-5057) upon impaired learning and memory in rodents. Psychopharmacology (Berl) . 1982;78 (2) :104-11.|[5]Nakamura K. Aniracetam: its novel therapeutic potential in cerebral dysfunctional disorders based on recent pharmacological discoveries. CNS Drug Rev. 2002 Spring;8 (1) :70-89.|[6]Pizzi M, et al. Attenuation of excitatory amino acid toxicity by metabotropic glutamate receptor agonists and aniracetam in primary cultures of cerebellar granule cells. J Neurochem. 1993 Aug;61 (2) :683-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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