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Lorundrostat

CAT: 1568-C01888-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:1568-C01888-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1820940-17-7
Synonyms
MT-4129
Target
P450 (e.g. CYP17)
Applications
Metabolism
Molecular Formula
C24H33N7O2
Additionnal Information
Lorundrostat (MT-4129) is a highly selective inhibitor of CYP11B2 (aldosterone synthase), with inhibition constant (Ki) values of 1.27 nM for hCYP11B2 and 475 nM for hCYP11B1. It demonstrates potential as a safe and effective treatment for aldosterone-dependent uncontrolled hypertension, including cases of treatment-resistant hypertension.

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