Products for Research Use Only
RegisterLogin

Exarafenib

CAT: 1568-C01780-25mgSize: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1568-C01780-25mgSize:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2639957-39-2
Synonyms
KIN-002787, KIN-2787, RAF/KIN_2787
Target
Raf
Applications
MAPK
Molecular Formula
C26H34F3N5O3
Additionnal Information
Exarafenib (KIN-002787, KIN-2787, RAF/KIN_2787) is an orally-available, selective inhibitor of pan-RAF. Exarafenib is effective in RAF-dependent cancers, including all classes of BRAF alterations. Exarafenib suppresses MAPK signaling in RAF-dependent melanoma cell lines. KIN-2787 exhibits low nanomolar to picomolar potency against RAF1, BRAF, and ARAF with an IC50 of 0.06-3.46 nM with minimal activity towards non-RAF kinases.

Alternative Products

CatalogName
BA6513-50Exarafenib

Popular Products