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Bexotegrast

CAT: 1568-C01650-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:1568-C01650-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2376257-44-0
Synonyms
PLN-74809
Target
Integrin
Applications
Cytoskeletal Signaling
Molecular Formula
C27H36N6O3
Additionnal Information
Bexotegrast (PLN-74809) is potent dual selective inhibitor of αvβ6 and αvβ1 integrins with Kd of 5.7 nM and 3.4 nM, respectively. It has antifibrogenic effects, blocks multiple TGF-β activation pathways in the fibrotic lung, and is useful for researching fibrosis, including idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP) .
Storage Conditions
2 years -20°C liquid