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DS18561882

CAT: 1568-C18296-25mgSize: 25 mgDry Ice: NoHazardous: No
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CAT#:1568-C18296-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2227149-22-4
Smiles
CS (=O) (NC1=CC=C (C (N2CCC (C3=CC=C (N4C[C@H] (C) N (C) CC4) C (C) =C3O5) =C (C5=O) C2) =O) C=C1OC (F) (F) F) =O
Molecular Formula
C28H31F3N4O6S
Additionnal Information
DS18561882 is a potent, isozyme-selective, and orally available inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) with an IC50 value of 0.0063 μM. It exhibits complete tumor growth inhibition in a mouse xenograft model, and shows potential as an anti-cancer agent.