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Ifebemtinib

CAT: 1568-C01482-100mgSize: 100 mgDry Ice: NoHazardous: No
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CAT#:1568-C01482-100mgSize:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1227948-82-4
Synonyms
IN-10018, BI-853520
Target
FAK
Applications
Protein Tyrosine Kinase
Molecular Formula
C28H28F4N6O4
Additionnal Information
Ifebemtinib (IN10018, BI853520) is a highly selective, potent inhibitor of focal adhesion kinase (FAK), with an IC50 of 1 nM for inhibiting FAK autophosphorylation. It also inhibits FER Kinase and FES Kinase with IC50s of 900 nM and 1040 nM, respectively, inhibiting spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma. IN10018 exhibits anti-tumor activity in vitro and in vivo.

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HY-122844BIfebemtinib (tosylate)
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A24190-10Ifebemtinib (BI-853520, IN-10018) 10mg
A24190-5Ifebemtinib (BI-853520, IN-10018) 5mg
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