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Leucylleucine methyl ester

CAT: 1568-C21564-50mgSize: 50 mgDry Ice: NoHazardous: No
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CAT#:1568-C21564-50mgSize:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
13022-42-9
Molecular Formula
C13H26N2O3 132623
Additionnal Information
Leucylleucine methyl ester is a lysosomotropic dipeptide that is taken up into leukocyte lysosomes via a dipeptide‐specific transport system and cleaved by the granule enzyme dipeptidyl peptidase I (cathepsin C) into hydrophobic oligomers, which disrupt intracellular membranes and selectively kill cytotoxic lymphocytes and other DPPI‐high cells, with species‐dependent sensitivity of B cells (murine B cells sensitive, human B cells largely resistant) .