Products for Research Use Only
RegisterLogin

MK-6884

CAT: 0804-HY-141899-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-141899-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2102194-04-5
UNSPSC Description
MK-6884 is a M4 muscarinic receptor positive allosteric modulator (PAM) with a Ki value of 0.19 nM. MK-6884 can be used for the research of the neurodegenerative diseases. MK-6884 can be conveniently radiolabeled with carbon-11 and as a positron emission tomography (PET) imaging agent[1].
Target Antigen
mAChR
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mk-6884.html
Solubility
THF : 3.33 mg/mL (ultrasonic)
Smiles
N#CC1=NC(C2=CC3=C(CN(C)C3=O)C=C2)=C(C4=CN(CC5(C)CCCC5)N=C4)C=C1
Molecular Weight
411.50
References & Citations
[1]Tong L, et al. Discovery of [11C]MK-6884: A Positron Emission Tomography (PET) Imaging Agent for the Study of M4Muscarinic Receptor Positive Allosteric Modulators (PAMs) in Neurodegenerative Diseases. J Med Chem. 2020;63(5):2411-2425.
Shipping Conditions
Room Temperature
Clinical Information
No Development Reported

Related Products

CatalogName
HY-RI02328-01Hsa-miR-6884-3p inhibitor
HY-R02328A-01Hsa-miR-6884-3p agomir
HY-R02328-01Hsa-miR-6884-3p mimic
HY-R02329A-01Hsa-miR-6884-5p agomir
HY-RI02328A-01Hsa-miR-6884-3p antagomir
HY-RI02329-01Hsa-miR-6884-5p inhibitor
HY-RI02329A-01Hsa-miR-6884-5p antagomir
HY-R02329-01Hsa-miR-6884-5p mimic
HY-P991581MK-2060
HY-P991406MK-1248

Alternative Products

CatalogName
BA5500-1MK-6884
T61878-01N-Demethyl MK-6884
MPH03794hsa-miR-6884-3p Primers
MPH03795hsa-miR-6884-5p Primers
MBS8313127-01hsa-miR-6884-3p miRNA Agomir
CMH2432-01Hsa-miR-6884-3p miRNA Mimic
mh42640LentimiRa-hsa-miR-6884-5p Vector
MNH03726hsa-miR-6884-5p miRNA Antagomir
MIH03725hsa-miR-6884-3p miRNA Inhibitor
324068-01MK

Popular Products