Noscapine base

CAT: 0926-FN09246-03Size: 100 gDry Ice: NoHazardous: No

1 / 1

CAT#:0926-FN09246-03Size:100 g

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

128-62-1

Synonyms

(3S) -6,7-Dimethoxy-3-[ (5R) -5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo [4, 5-g]isoquinolin-5-yl] phthalide

MDL Number

MFCD00127721

Smiles

CN1CCC2=CC3=C (C (=C2[C@@H]1[C@@H]4C5=C (C (=C (C=C5) OC) OC) C (=O) O4) OC) OCO3

Molecular Formula

C22H23NO7

Molecular Weight

413.43 g/mol

Controlled

Chemical Information

Noscapine

(-)-noscapine is a benzylisoquinoline alkaloid that is 1,2,3,4-tetrahydroisoquinoline which is substituted by a 4,5-dimethoxy-3-oxo-1,3-dihydro-2-benzofuran-1-yl group at position 1, a methylenedioxy group at positions 6-7 and a methoxy group at position 8. Obtained from plants of the Papaveraceae family, it lacks significant painkilling properties and is primarily used for its antitussive (cough-suppressing) effects. It has a role as an antineoplastic agent, an antitussive, an apoptosis inducer and a plant metabolite. It is a benzylisoquinoline alkaloid, an organic heterotricyclic compound, an organic heterobicyclic compound, an aromatic ether, a tertiary amino compound, an isobenzofuranone and a cyclic acetal. It is functionally related to a (-)-noscapine hemiacetal.

CAS Number	128-62-1
PubChem CID	275196
IUPAC Name	(3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one
Molecular Formula	C22H23NO7
Molecular Weight	413.4
XLogP	2.7
Topological Polar Surface Area	75.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Heavy Atom Count	30
Formal Charge	0
Complexity	647

SMILES

CN1CCC2=CC3=C(C(=C2[C@@H]1[C@@H]4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3

InChI

InChI=1S/C22H23NO7/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18/h5-6,9,17-18H,7-8,10H2,1-4H3/t17-,18+/m1/s1

InChIKey

AKNNEGZIBPJZJG-MSOLQXFVSA-N

Chemical Structure

2D Structure

CAS: 128-62-1

CID: 275196

Formula: C22H23NO7

MW: 413.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	413.4
XLogP3	2.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Exact Mass	413.14745207
Monoisotopic Mass	413.14745207
Topological Polar Surface Area	75.7 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	647
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
FN30697-01	Noscapine hydrochloride hydrate
SYB68057-01	Noscapine-13C, d3
FA61536-01	Amlodipine base
FD22602-01	Dovitinib base
BE164419-01	Erlotinib base
FP39372-01	Pioglitazone base
FM10813-01	Imatinib base
FM01545	Metoclopramide base
FD32120-01	Sunitinib base
FP52727-01	Pararosaniline base

Alternative Products

Catalog	Name
285001-01	Noscapine base
MBS5758806-01	Noscapine
A8479-1000	Noscapine HCl
HY-13716R-01	Noscapine (Standard)
460955-01	Noscapine Hydrochloride
HY-13716A-01	Noscapine (hydrochloride)

Noscapine base

Chemical Information

Related Products

Alternative Products

Popular Products