AZD 9291 mesylate

CAT: 0926-FD146297-01Size: 0.1 gDry Ice: NoHazardous: No

1 / 1

CAT#:0926-FD146297-01Size:0.1 g

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1421373-66-1

Synonyms

N-· (2-· ((2-· (Dimethylamino) ethyl) (methyl) amino) - 4- methoxy- 5- ((4- (1- methyl- 1H- indol- 3- yl) pyrimidin- 2- yl) amino) phen yl) acrylamide methanesulfonate; Osimertinib mesylate; Mereletinib mesylate

MDL Number

MFCD28137994

Smiles

CN1C=C (C2=CC=CC=C21) C3=NC (=NC=C3) NC4=C (C=C (C (=C4) NC (=O) C=C) N (C) CCN (C) C) OC.CS (=O) (=O) O

Molecular Formula

C28H33N7O2·CH4O3S

Controlled

Chemical Information

Osimertinib Mesylate

Osimertinib mesylate is a methanesulfonate (mesylate) salt prepared from equimolar amounts of osimertinib and methanesulfonic acid. It is used for treatment of EGFR T790M mutation positive non-small cell lung cancer. It has a role as an antineoplastic agent and an epidermal growth factor receptor antagonist. It contains an osimertinib(1+).

CAS Number	1421373-66-1
PubChem CID	78357807
IUPAC Name	N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide;methanesulfonic acid
Molecular Formula	C29H37N7O5S
Molecular Weight	595.7
Topological Polar Surface Area	150
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	10
Heavy Atom Count	42
Formal Charge	0
Complexity	845

SMILES

CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC.CS(=O)(=O)O

InChI

InChI=1S/C28H33N7O2.CH4O3S/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24;1-5(2,3)4/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32);1H3,(H,2,3,4)

InChIKey

FUKSNUHSJBTCFJ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1421373-66-1

CID: 78357807

Formula: C29H37N7O5S

MW: 595.7

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	595.7
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	10
Exact Mass	595.25768848
Monoisotopic Mass	595.25768848
Topological Polar Surface Area	150 Å²
Heavy Atom Count	42
Formal Charge	0
Complexity	845
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	2
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
FD58317-01	AZD 9291
PCC21769-01	Azd-8529 mesylate
NC44330-01	AZD 1480
HEC15881-01	AZD-26
ULB35141-01	AZD 1283
WBC27045-01	AZD 8186
FE18067-01	AZD 1152
TQC80954-01	AZD 6642
FA64951-01	AZD 4547
FA153806-01	AZD 2858

Alternative Products

Catalog	Name
474070	AZD 9291 mesylate
441992-01	AZD-9291 Mesylate
MBS132733-01	AZD 9291
A2580-01	AZD-9291

AZD 9291 mesylate

Chemical Information

Related Products

Alternative Products

Popular Products