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Palm-PrRP31

CAT: 0804-HY-P10379Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10379Size:1 Each
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Description
Palm-PrRP31 is a potent dual receptor agonist for both GPR10 (EC50=72 pM) and NPFF-R2. palm-PrRP31 activates downstream signaling pathways through binding to its receptors, GPR10 and NPFF-R2, which results in reduced appetite and increased energy expenditure. Utilizing palm-PrRP31 facilitates the study of the mechanism of action in the nervous system, thereby elucidating the complex biological processes that regulate appetite and energy expenditure[1].
UNSPSC
12352209
Target
Neuropeptide FF Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Others
Assay Protocol
https://www.medchemexpress.com/palm-prrp31.html
Smiles
O=C([C@@H](NC(CCCCCCCCCCCCCCC)=O)CO)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N)=O)CC4=CC=CC=C4)=O)CCCNC(N)=N)=O)=O)C(C)C)=O)CCC3)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)=O)CCCNC(N)=N)=O)CO)=O)C)=O)CC5=CC=C(O)C=C5)=O)CC6=CNC7=CC=CC=C67)=O)C)=O)CCC2)=O)CC(N)=O)=O)[C@H](CC)C)=O)CC(O)=O)=O)CCC1)=O)[C@@H](C)O)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCSC)=O)CO)=O)CC8=CNC=N8)=O)CCCNC(N)=N)=O)CC9=CNC=N9)=O)[C@@H](C)O)=O)CCCNC(N)=N
Molecular Formula
C176H282N56O43S
Molecular Weight
3902.54
References & Citations
[1]Strnadová V, et al. Search for lipidized PrRP analogs with strong anorexigenic effect: in vitro and in vivo studies[J]. Neuropeptides, 2023, 98: 102319.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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