palm-PrRP31

palm-PrRP31

• UNSPSC Description: palm-PrRP31 is a potent dual receptor agonist for both GPR10 (EC50=72 pM) and NPFF-R2. palm-PrRP31 activates downstream signaling pathways through binding to its receptors, GPR10 and NPFF-R2, which results in reduced appetite and increased energy expenditure. Utilizing palm-PrRP31 facilitates the study of the mechanism of action in the nervous system, thereby elucidating the complex biological processes that regulate appetite and energy expenditure[1].
• Target Antigen: Neuropeptide FF Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease; Others
• Assay Protocol: https://www.medchemexpress.com/palm-prrp31.html
• Smiles: O=C([C@@H](NC(CCCCCCCCCCCCCCC)=O)CO)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N)=O)CC4=CC=CC=C4)=O)CCCNC(N)=N)=O)=O)C(C)C)=O)CCC3)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)=O)CCCNC(N)=N)=O)CO)=O)C)=O)CC5=CC=C(O)C=C5)=O)CC6=CNC7=CC=CC=C67)=O)C)=O)CCC2)=O)CC(N)=O)=O)[C@H](CC)C)=O)CC(O)=O)=O)CCC1)=O)[C@@H](C)O)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCSC)=O)CO)=O)CC8=CNC=N8)=O)CCCNC(N)=N)=O)CC9=CNC=N9)=O)[C@@H](C)O)=O)CCCNC(N)=N
• Molecular Weight: 3902.54
• References & Citations: [1]Strnadová V, et al. Search for lipidized PrRP analogs with strong anorexigenic effect: in vitro and in vivo studies[J]. Neuropeptides, 2023, 98: 102319.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported