2-Iodoacetamide

• Description :

  2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics[1][2].

• Product Name Alternative :

  Iodoacetamide

• UNSPSC :

  12352211

• Hazard Statement :

  H301, H317, H334, H413

• Target :

  DNA Alkylator/Crosslinker

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/2-iodoacetamide.html

• Purity :

  99.62

• Solubility :

  DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(N)CI

• Molecular Formula :

  C2H4INO

• Molecular Weight :

  184.96

• Precautions :

  H301, H317, H334, H413

• References & Citations :

  [1]Peter G Hains, et al. The Impact of Commonly Used Alkylating Agents on Artifactual Peptide Modification. J Proteome Resq. 2017 Sep 1;16 (9) :3443-3447.|[2]J J LALICH. Iodoacetamide induced gastric ulcers in rats. Proc Soc Exp Biol Med. 1962 Apr;109:905-8.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [144-48-9]