trans-Boronic acid pinacol-pyrazole-C-cyclobutane-O-piperidine-Boc

• UNSPSC Description:

  trans-Boronic acid pinacol-pyrazole-C-cyclobutane-O-piperidine-Boc is a PROTAC linker. trans-Boronic acid pinacol-pyrazole-C-cyclobutane-O-piperidine-Boc can be used in the synthesis of PROTAC SMARCA2/4-degrader-35 (HY-168225)[1].

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/trans-boronic-acid-pinacol-pyrazole-c-cyclobutane-o-piperidine-boc.html

• Smiles:

  O=C(OC(C)(C)C)N(CC1)CCC1O[C@@H](C2)C[C@H]2CN3N=CC(B4OC(C)(C)C(C)(C)O4)=C3

• Molecular Weight:

  461.40

• References & Citations:

  [1]Michael Berlin, et al. Brm targeting compounds and associated methods of use. WO, WO2023096987. 2023-06-01.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 3

• CAS Number:

  2933254-71-6