T807

CAT: 0804-HY-101184-02Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-101184-02Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

T807 a novel tau positron emission tomography (PET) tracer.

CAS Number

1415379-56-4

Product Name Alternative

AV-1451

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Tau Protein

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/T807.html

Purity

99.21

Solubility

DMSO : ≥ 16.6 mg/mL

Smiles

FC1=CC=C(C2=CC3=C(C=C2)C(C=NC=C4)=C4N3)C=N1

Molecular Formula

C16H10FN3

Molecular Weight

263.27

Precautions

H302, H315, H319, H335

References & Citations

[1]Xia CF, et al. [ (18) F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease. Alzheimers Dement. 2013 Nov;9 (6) :666-76.|[2]Marquié M, et al. Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue. Ann Neurol. 2015 Nov;78 (5) :787-800.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Chemical Information

Flortaucipir

Flortaucipir is under investigation in clinical trial NCT03507257 (Longitudinal Early-onset Alzheimer's Disease Study Protocol).

CAS Number	1415379-56-4
PubChem CID	71059746
IUPAC Name	7-(6-fluoro-3-pyridinyl)-5H-pyrido[4,3-b]indole
Molecular Formula	C16H10FN3
Molecular Weight	263.27
XLogP	3.3
Topological Polar Surface Area	41.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Heavy Atom Count	20
Formal Charge	0
Complexity	351

SMILES

C1=CC2=C(C=C1C3=CN=C(C=C3)F)NC4=C2C=NC=C4

InChI

InChI=1S/C16H10FN3/c17-16-4-2-11(8-19-16)10-1-3-12-13-9-18-6-5-14(13)20-15(12)7-10/h1-9,20H

InChIKey

GETAAWDSFUCLBS-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1415379-56-4

CID: 71059746

Formula: C16H10FN3

MW: 263.27

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	263.27
XLogP3	3.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	263.08587549
Monoisotopic Mass	263.08587549
Topological Polar Surface Area	41.6 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	351
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
HY-101185	T808
HY-112624Q-01	Dextran T800 (MW 800,000)

Alternative Products

Catalog	Name
T19573-01	T807
A20538-200	T807 200mg
A20538-25	T807 25mg
A20538-10	T807 10mg
A20538-5	T807 5mg
A20538-100	T807 100mg
A20538-50	T807 50mg
A20538-500	T807 500mg
A20538-2	T807 2mg

T807

Chemical Information

Related Products

Alternative Products

Popular Products