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NU2058

CAT: 0957-S5316-25mgSize: 25 mgDry Ice: YesHazardous: No
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CAT#:0957-S5316-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
161058-83-9
Synonyms
O (6) -Cyclohexylmethylguanine
Target
CDK
Applications
Cell Cycle
Smiles
C1CCC (CC1) COC2=NC (=NC3=C2NC=N3) N
Molecular Formula
C12H17N5O
Additionnal Information
NU2058 (O (6) -Cyclohexylmethylguanine) is an inhibitor of CDK2 with IC50 value of 17 μM in an isolated enzyme assay. It also potentiates melphalan (DMF 2.3), and monohydroxymelphalan (1.7), but not temozolomide or ionising radiation.
Storage Conditions
2 years -80 in solvent