Galeterone

CAT: 0957-S2803-50mgSize: 50 mgDry Ice: YesHazardous: No

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CAT#:0957-S2803-50mgSize:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

851983-85-2

Synonyms

TOK-001

Target

Androgen Receptor

Applications

Endocrinology & Hormones

Smiles

CC12CCC (CC1=CCC3C2CCC4 (C3CC=C4N5C=NC6=CC=CC=C65) C) O

Molecular Formula

C26H32N2O

Additionnal Information

Galeterone (TOK-001) is a selective CYP17 inhibitor and androgen receptor (AR) antagonist with IC50 of 300 nM and 384 nM, respectively, and is a potent inhibitor of human prostate tumor growth. Phase 2.

Storage Conditions

2 years -80 in solvent

Chemical Information

Galeterone

Galeterone is a 3-hydroxy steroid. It has a role as an androgen.

CAS Number	851983-85-2
PubChem CID	11188409
IUPAC Name	(3S,8R,9S,10R,13S,14S)-17-(benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol
Molecular Formula	C26H32N2O
Molecular Weight	388.5
XLogP	5.2
Topological Polar Surface Area	38.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Heavy Atom Count	29
Formal Charge	0
Complexity	743

SMILES

C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4N5C=NC6=CC=CC=C65)C)O

InChI

InChI=1S/C26H32N2O/c1-25-13-11-18(29)15-17(25)7-8-19-20-9-10-24(26(20,2)14-12-21(19)25)28-16-27-22-5-3-4-6-23(22)28/h3-7,10,16,18-21,29H,8-9,11-15H2,1-2H3/t18-,19-,20-,21-,25-,26-/m0/s1

InChIKey

PAFKTGFSEFKSQG-PAASFTFBSA-N

Chemical Structure

2D Structure

CAS: 851983-85-2

CID: 11188409

Formula: C26H32N2O

MW: 388.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	388.5
XLogP3	5.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	388.251463648
Monoisotopic Mass	388.251463648
Topological Polar Surface Area	38.1 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	743
Isotope Atom Count	0
Defined Atom Stereocenter Count	6
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
FT65187-01	Galeterone
CS-T-103430	Galeterone-d4
HY-70006A	Galeterone (hydrochloride)
RM-G123801-01	Galeterone Impurity 1
A11138-25	TOK-001 (Galeterone) 25mg
MBS386374-01	TOK-001 (Galeterone)
6108/10	Galeterone 10 mg
6108/50	Galeterone 50 mg

Galeterone

Chemical Information

Alternative Products

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