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AG-1478

CAT: 0957-S2728-10mgSize: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S2728-10mgSize:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
153436-53-4,175178-82-2
Synonyms
Tyrphostin AG-1478, NSC 693255
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
COC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC (=CC=C3) Cl) OC
Molecular Formula
C16H14ClN3O2
Additionnal Information
AG-1478 is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. AG-1478 (Tyrphostin AG-1478) inhibits encephalomyocarditis virus (EMCV) and hepatitis c virus (HCV) by targeting phosphatidylinositol 4-kinase IIIα (PI4KA) .
Storage Conditions
2 years -80 in solvent

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