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WYE-687

CAT: 0957-S2668-50mgSize: 50 mgDry Ice: YesHazardous: No
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CAT#:0957-S2668-50mgSize:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1062161-90-3
Target
MTOR
Applications
PI3K/Akt/mTOR
Smiles
COC (=O) NC1=CC=C (C=C1) C2=NC3=C (C=NN3C4CCN (CC4) CC5=CN=CC=C5) C (=N2) N6CCOCC6
Molecular Formula
C28H32N8O3
Additionnal Information
WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K (T389) and mTORC2/P-AKT (S473) but no effect observed on P-AKT (T308) . Selectivity for mTOR is greater than PI3Kα (>100-fold) and PI3Kγ (>500-fold) .
Storage Conditions
2 years -80 in solvent

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Alternative Products

CatalogName
022895WYE-687
MBS132286-01WYE 687

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