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Itraconazole

CAT: 0957-S2476-100mgSize: 100 mgDry Ice: YesHazardous: No
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CAT#:0957-S2476-100mgSize:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
84625-61-6
Synonyms
R 51211
Target
Hedgehog/Smoothened
Applications
Stem Cells & Wnt
Smiles
CCC (C) N1C (=O) N (C=N1) C2=CC=C (C=C2) N3CCN (CC3) C4=CC=C (C=C4) OCC5COC (O5) (CN6C=NC=N6) C7=C (C=C (C=C7) Cl) Cl
Molecular Formula
C35H38Cl2N8O4
Additionnal Information
Itraconazole is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.
Storage Conditions
2 years -80 in solvent

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