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CYC116

CAT: 0957-S1171-10mM/1mLSize: 10 mM/1mLDry Ice: YesHazardous: No
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CAT#:0957-S1171-10mM/1mLSize:10 mM/1mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
693228-63-6
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
CC1=C (SC (=N1) N) C2=NC (=NC=C2) NC3=CC=C (C=C3) N4CCOCC4
Molecular Formula
C18H20N6OS
Additionnal Information
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 and SAPK2A. Phase 1.
Storage Conditions
2 years -80 in solvent

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A4125-10CYC116
A10248-50CYC116 50mg
A10248-25CYC116 25mg
A10248-5CYC116 5mg
A10248-100CYC116 100mg
A10248-2CYC116 2mg
A10248-500CYC116 500mg
A10248-10CYC116 10mg
MBS384575-01CYC116 (CYC-116)
A10248-10mM-DCYC116 10mM * 1mL in DMSO

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