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JY-2

CAT: 0957-E6471-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:0957-E6471-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
339103-05-8
Target
FOX
Applications
Metabolism
Molecular Formula
C13H7Cl2N3O
Additionnal Information
JY-2 is a selective and orally active inhibitor of the transcription factor forkhead box O1 (FoxO1) . JY-2 suppresses FoxO1-driven transcriptional activity with an IC50 of 22 μM, and also exerts moderate inhibitory effects on FoxO3a and FoxO4. JY-2 also exhibits anti-diabetic properties.

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