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BAY1125976

CAT: 0957-S8500-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S8500-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1402608-02-9
Target
Akt
Applications
PI3K/Akt/mTOR
Smiles
C1CC (C1) (C2=CC=C (C=C2) C3=C (N4C (=N3) C=CC (=N4) C (=O) N) C5=CC=CC=C5) N
Molecular Formula
C23H21N5O
Additionnal Information
BAY 1125976 is a selective allosteric AKT1/2 inhibitor, exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models. BAY1125976 inhibits the activity of AKT1 (IC50 = 5.2 nM at 10 μM ATP and 44 nM at 2 mM ATP) and AKT2 (IC50 = 18 nM at 10 μM ATP and 36 nM at 2 mM ATP) very potently.Whereas BAY1125976 is almost inactive on AKT3 (IC50 = 427 nM at 10 μM ATP) .
Storage Conditions
3 years -20°C powder

Alternative Products

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BA8674-5BAY1125976
A20421-5BAY1125976 5mg
A20421-500BAY1125976 500mg
A20421-50BAY1125976 50mg
A20421-25BAY1125976 25mg
HY-100018RBAY1125976 (Standard)
A20421-2BAY1125976 2mg
A20421-1BAY1125976 1mg
A20421-100BAY1125976 100mg
A20421-10BAY1125976 10mg

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