TAK-243 (MLN7243)

CAT: 0957-S8341-2mgSize: 2 mgDry Ice: NoHazardous: No

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CAT#:0957-S8341-2mgSize:2 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1450833-55-2

Target

E1 Activating

Applications

Ubiquitin

Smiles

N[S; v6] (=O) (=O) OCC1CC (NC2=CC=NC3=CC (=N[N]23) C4=CC (=CC=C4) SC (F) (F) F) C (O) C1O

Molecular Formula

C19H20F3N5O5S2

Additionnal Information

TAK-243 (MLN7243) is a potent, mechanism-based small-molecule inhibitor of the ubiquitin activating enzyme (UAE) with an IC50 of 1 ± 0.2 nM in the UBCH10 E2 thioester assay. It has minimal inhibitory activity in a panel of kinase and receptor assays, as well as on human carbonic anhydrase type I and type II. TAK-243 (MLN7243) induces ER stress, abrogates NFκB pathway activation and promotes apoptosis.

Storage Conditions

3 years -20°C powder

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Catalog	Name
C13356-01	TAK-243 (MLN7243)
bs-60332C-01	TAK-243 (MLN7243), Ubiquitin Activating Enzyme (UAE) Inhibitor
BT165712-01	TAK 243
HY-100487-01	TAK-243
A20369-10	TAK-243 10mg
A20369-5	TAK-243 5mg
A20369-1	TAK-243 1mg
A20369-100	TAK-243 100mg
A20369-50	TAK-243 50mg
A20369-2	TAK-243 2mg

TAK-243 (MLN7243)

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