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BML-284 (Wnt agonist 1)

CAT: 0957-S8178-10mM/1mLSize: 10 mM/1mLDry Ice: YesHazardous: No
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CAT#:0957-S8178-10mM/1mLSize:10 mM/1mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2095432-75-8
Synonyms
AMBMP
Target
Wnt/beta-catenin
Applications
Cytoskeletal Signaling
Smiles
COC1=CC=CC (=C1) C2=CC (=NC (=N2) N) NCC3=CC4=C (C=C3) OCO4.Cl
Molecular Formula
C19H18N4O3·HCl
Additionnal Information
BML-284 (Wnt agonist 1) is a cell permeable Wnt signaling pathway activator, which induces β-catenin- and TCF-dependent transcriptional activity with EC50 of 0.7 μM.
Storage Conditions
2 years -80 in solvent

Chemical Information

AMBMP hydrochloride
CAS Number2095432-75-8
PubChem CID122705993
IUPAC Name4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine;hydrochloride
Molecular FormulaC19H19ClN4O3
Molecular Weight386.8
Topological Polar Surface Area91.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Heavy Atom Count27
Formal Charge0
Complexity455
SMILES
COC1=CC=CC(=C1)C2=CC(=NC(=N2)N)NCC3=CC4=C(C=C3)OCO4.Cl
InChI
InChI=1S/C19H18N4O3.ClH/c1-24-14-4-2-3-13(8-14)15-9-18(23-19(20)22-15)21-10-12-5-6-16-17(7-12)26-11-25-16;/h2-9H,10-11H2,1H3,(H3,20,21,22,23);1H
InChIKey
XZOFNDFDGVAIEH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of AMBMP hydrochloride
CAS: 2095432-75-8
CID: 122705993
Formula: C19H19ClN4O3
MW: 386.8
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight386.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass386.1145682
Monoisotopic Mass386.1145682
Topological Polar Surface Area91.5 Ų
Heavy Atom Count27
Formal Charge0
Complexity455
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes