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GANT61

CAT: 0957-S8075-10mgSize: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S8075-10mgSize:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
500579-04-4
Synonyms
NSC 136476
Target
Hedgehog/Smoothened
Applications
Stem Cells & Wnt
Smiles
CN (C) C1=CC=CC=C1CN2CCCN (C2C3=CC=NC=C3) CC4=CC=CC=C4N (C) C
Molecular Formula
C27H35N5
Additionnal Information
GANT61 (NSC 136476) is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM in GLI1 expressing HEK293T cell, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation. GANT61 induces apoptosis and activates protective autophagy in LX-2 cells.
Storage Conditions
2 years -80 in solvent

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A1615-5.1GANT61
A13252-500GANT61 500mg
A13252-50GANT61 50mg
A13252-2GANT61 2mg
A13252-25GANT61 25mg
A13252-10GANT61 10mg
A13252-100GANT61 100mg

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