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Poziotinib

CAT: 0957-S7358-1gSize: 1 gDry Ice: YesHazardous: No
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CAT#:0957-S7358-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1092364-38-9
Synonyms
HM781-36B, NOV120101
Target
HER2
Applications
Protein Tyrosine Kinase
Smiles
COC1=C (C=C2C (=C1) N=CN=C2NC3=C (C (=C (C=C3) Cl) Cl) F) OC4CCN (CC4) C (=O) C=C
Molecular Formula
C23H21Cl2FN4O3
Additionnal Information
Poziotinib is an irreversible pan-HER inhibitor with IC50 of 3.2 nM, 5.3 nM and 23.5 nM for HER1, HER2, and HER4, respectively. Poziotinib also induces apoptosis and G1 cell cycle arrest. Phase 2.
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
T2630-01Poziotinib
BP168498-01Poziotinib hydrochloride
A13044-25Poziotinib 25mg
A13044-5Poziotinib 5mg

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