Products for Research Use Only

GW441756

CAT: 0957-S2891-1gSize: 1 gDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0957-S2891-1gSize:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
504433-23-2
Target
Trk receptor
Applications
Protein Tyrosine Kinase
Smiles
CN1C=C (C2=CC=CC=C21) C=C3C4=C (C=CC=N4) NC3=O
Molecular Formula
C17H13N3O
Additionnal Information
GW441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM, with very little activity to c-Raf1 and CDK2. GW441756 produces a relevant increase of caspase-3 that leads to apoptosis.
Storage Conditions
2 years -80 in solvent