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Capmatinib

CAT: 0957-S2788-10mgSize: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S2788-10mgSize:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1029712-80-8
Synonyms
INC280, NVP-INC280, INCB28060
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
CNC (=O) C1=C (C=C (C=C1) C2=NN3C (=CN=C3N=C2) CC4=CC5=C (C=C4) N=CC=C5) F
Molecular Formula
C23H17FN6O
Additionnal Information
Capmatinib is a novel, ATP-competitive inhibitor of c-MET with IC50 of 0.13 nM in a cell-free assay, inactive against RONβ, as well as EGFR and HER-3. Capmatinib (INCB28060) inhibits Wnt/β-catenin and EMT signaling pathways and induces apoptosis in diffuse gastric cancer positive for c-MET amplification. Phase 1.
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
C08858-50mgCapmatinib
HY-13404R-01Capmatinib (Standard)
BUP09131-01Capmatinib xHCl
CS-EO-02512Capmatinib D3
HY-13404A-01Capmatinib (dihydrochloride)
MBS3607865-01Capmatinib 2HCl
MBS3612843-01Capmatinib hydrochloride

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