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MK-2461

CAT: 0957-S2774-5mgSize: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2774-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
917879-39-1
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
CN1C=C (C=N1) C2=CC3=C (C=CC4=C (C3=O) C=C (C=C4) NS (=O) (=O) N (C) CC5COCCO5) N=C2
Molecular Formula
C24H25N5O5S
Additionnal Information
MK-2461 is a potent, multi-targeted inhibitor for c-Met (WT/mutants) with IC50 of 0.4-2.5 nM, less potent to Ron, Flt1; 8- to 30-fold greater selectivity of c-Met targets versus FGFR1, FGFR2, FGFR3, PDGFRβ, KDR, Flt3, Flt4, TrkA, and TrkB. Phase 1/2.
Storage Conditions
2 years -80 in solvent

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