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Ponatinib

CAT: 0957-S1490-1gSize: 1 gDry Ice: YesHazardous: No
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CAT#:0957-S1490-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
943319-70-8
Synonyms
AP24534
Target
Bcr-Abl
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C=C (C=C1) C (=O) NC2=CC (=C (C=C2) CN3CCN (CC3) C) C (F) (F) F) C#CC4=CN=C5N4N=CC=C5
Molecular Formula
C29H27F3N6O
Additionnal Information
Ponatinib is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively. Ponatinib (AP24534) inhibits autophagy.
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
202320Ponatinib

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