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Nutlin-3

CAT: 0957-S1061-1gSize: 1 gDry Ice: YesHazardous: No
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CAT#:0957-S1061-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
890090-75-2
Target
E3 Ligase
Applications
Ubiquitin
Smiles
CC (C) OC1=C (C=CC (=C1) OC) C2=NC (C (N2C (=O) N3CCNC (=O) C3) C4=CC=C (C=C4) Cl) C5=CC=C (C=C5) Cl
Molecular Formula
C30H30Cl2N4O4
Additionnal Information
Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells.
Storage Conditions
2 years -80 in solvent

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