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Rapamycin

CAT: 0957-S1039-10mM/1mLSize: 10 mM/1mLDry Ice: YesHazardous: No
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CAT#:0957-S1039-10mM/1mLSize:10 mM/1mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
53123-88-9
Synonyms
Sirolimus, AY-22989, NSC-2260804
Target
Autophagy
Applications
Autophagy
Smiles
CC1CCC2CC (C (=CC=CC=CC (CC (C (=O) C (C (C (=CC (C (=O) CC (OC (=O) C3CCCCN3C (=O) C (=O) C1 (O2) O) C (C) CC4CCC (C (C4) OC) O) C) C) O) OC) C) C) C) OC
Molecular Formula
C51H79NO13
Additionnal Information
Rapamycin is a specific mTOR inhibitor with IC50 of ~0.1 nM in HEK293 cells.Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator and an immunosuppressant.
Storage Conditions
2 years -80 in solvent

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