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CPYPP

CAT: 0957-S0899-10mM/1mLSize: 10 mM/1mLDry Ice: NoHazardous: No
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CAT#:0957-S0899-10mM/1mLSize:10 mM/1mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
310460-39-0
Target
DOCK
Applications
Cell Cycle
Smiles
C1=CC=C (C=C1) N2C (=O) C (=CC=CC3=CC=CC=C3Cl) C (=O) N2
Molecular Formula
C18H13ClN2O2
Additionnal Information
CPYPP is an inhibitor of dedicator of cytokinesis 2 (DOCK2) . CPYPP inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner with IC50 of 22.8 μM. CPYPP also inhibits DOCK180, DOCK5 and less DOCK9.
Storage Conditions
3 years -20°C powder

Chemical Information

Cpypp
CAS Number310460-39-0
PubChem CID2248186
IUPAC Name(4E)-4-[(E)-3-(2-chlorophenyl)prop-2-enylidene]-1-phenylpyrazolidine-3,5-dione
Molecular FormulaC18H13ClN2O2
Molecular Weight324.8
XLogP4.1
Topological Polar Surface Area49.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Heavy Atom Count23
Formal Charge0
Complexity523
SMILES
C1=CC=C(C=C1)N2C(=O)/C(=C/C=C/C3=CC=CC=C3Cl)/C(=O)N2
InChI
InChI=1S/C18H13ClN2O2/c19-16-12-5-4-7-13(16)8-6-11-15-17(22)20-21(18(15)23)14-9-2-1-3-10-14/h1-12H,(H,20,22)/b8-6+,15-11+
InChIKey
VVZJFICTTKPNCK-KVDBUQHUSA-N
Chemical Structure
2D Structure
2D structure of Cpypp
CAS: 310460-39-0
CID: 2248186
Formula: C18H13ClN2O2
MW: 324.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight324.8
XLogP34.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass324.0665554
Monoisotopic Mass324.0665554
Topological Polar Surface Area49.4 Ų
Heavy Atom Count23
Formal Charge0
Complexity523
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA5956-5.1CPYPP
4568/50CPYPP 50 mg
4568/10CPYPP 10 mg

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