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MAZ51

CAT: 0957-S0765-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:0957-S0765-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
163655-37-6
Target
VEGFR
Applications
Protein Tyrosine Kinase
Smiles
CN (C) C1=CC=C (C2=CC=CC=C21) C=C3C4=CC=CC=C4NC3=O
Molecular Formula
C21H18N2O
Additionnal Information
MAZ51 is a potent and selective inhibitor of vascular endothelial growth factor receptor (VEGFR) -3 (Flt-4) tyrosine kinase. MAZ51 induces cell rounding and G2/M cell cycle arrest in glioma cells through phosphorylation of Akt/GSK3β and activation of RhoA. MAZ51 inhibits the proliferation and induces the apoptosis of a variety of non-VEGFR-3-expressing tumor cell lines.
Storage Conditions
3 years -20°C powder

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