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E260

CAT: 0957-S0012-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S0012-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1241537-79-0
Synonyms
Fer and FerT inhibitor E260
Target
Fer kinase
Applications
Protein Tyrosine Kinase
Smiles
CC (C) C1=CC=C (C=C1) C2=CN3C (=N2) SC (=N3) N4CCC (CC4) CN5CCN (CC5) C
Molecular Formula
C24H34N6S
Additionnal Information
E260 (Fer and FerT inhibitor E260) is a Fer kinase and FerT inhibitor that selectively evokes metabolic stress in cancer cells by imposing mitochondrial dysfunction and deformation, and onset of energy-consuming autophagy which decreases the cellular ATP level.
Storage Conditions
3 years -20°C powder

Chemical Information

6-(4-Isopropylphenyl)-2-(4-((4-methylpiperazin-1-yl)methyl)piperidin-1-yl)imidazo[2,1-b][1,3,4]thiadiazole
CAS Number1241537-79-0
PubChem CID46898309
IUPAC Name2-[4-[(4-methylpiperazin-1-yl)methyl]piperidin-1-yl]-6-(4-propan-2-ylphenyl)imidazo[2,1-b][1,3,4]thiadiazole
Molecular FormulaC24H34N6S
Molecular Weight438.6
XLogP4.7
Topological Polar Surface Area68.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Heavy Atom Count31
Formal Charge0
Complexity566
SMILES
CC(C)C1=CC=C(C=C1)C2=CN3C(=N2)SC(=N3)N4CCC(CC4)CN5CCN(CC5)C
InChI
InChI=1S/C24H34N6S/c1-18(2)20-4-6-21(7-5-20)22-17-30-23(25-22)31-24(26-30)29-10-8-19(9-11-29)16-28-14-12-27(3)13-15-28/h4-7,17-19H,8-16H2,1-3H3
InChIKey
RFHSWNJYHRAOMP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 6-(4-Isopropylphenyl)-2-(4-((4-methylpiperazin-1-yl)methyl)piperidin-1-yl)imidazo[2,1-b][1,3,4]thiadiazole
CAS: 1241537-79-0
CID: 46898309
Formula: C24H34N6S
MW: 438.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight438.6
XLogP34.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass438.25656628
Monoisotopic Mass438.25656628
Topological Polar Surface Area68.2 Ų
Heavy Atom Count31
Formal Charge0
Complexity566
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
T4638-01E260
A17247-100E260 100mg
A17247-25E260 25mg
A17247-50E260 50mg
A17247-10E260 10mg
A17247-5E260 5mg
A17247-1E260 1mg
533067Fer/FerT inhibitor E260

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