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Certepetide

CAT: 0957-E8285-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E8285-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2580154-02-3
Synonyms
CEND-1; iRGD; LSTA1
Target
Immunology & Inflammation related
Applications
Immunology & Inflammation
Additionnal Information
Certepetide is a cyclic peptide that enhances delivery of coadministered anticancer drugs and modulates the tumor microenvironment. It binds αvβ3/5-integrins on tumor endothelium, undergoes proteolytic cleavage, and the resulting fragment binds neuropilin-1, triggering active tumor-specific drug transport. It also depletes immunosuppressive T cells, enhances cytotoxic T cells, and inhibits metastasis.

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