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Propargyl-PEG1-acid

CAT: 0957-E8079-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:0957-E8079-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
55683-37-9
Additionnal Information
Propargyl-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-CRBN PROTACs Ibrutinib (HY-10997) -based PROTAC 4 and PROTAC 5. PROTAC 5 causes the degradation of BTK and induces the degradation of CSK, LYN, and LAT2 at 10 μM. Propargyl-PEG1-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent

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