TD52

CAT: 0957-E8041-5mgSize: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0957-E8041-5mgSize:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1798328-24-1

Additionnal Information

TD52, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 has less p-EGFR inhibition and has potent anti-cancer activity. TD52 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

Alternative Products

Catalog	Name
M28041-01	TD52
HY-135699A-01	TD52 (dihydrochloride)
BUP06586-01	TD52 dihydrochloride

TD52

Alternative Products

Popular Products