Products for Research Use Only
RegisterLogin

L67

CAT: 0957-E7688-5mgSize: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-E7688-5mgSize:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
325970-71-6
Synonyms
DNA Ligase Inhibitor
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Molecular Formula
C16H14Br2N4O4
Additionnal Information
L67 (DNA Ligase Inhibitor) is a competitive inhibitor of DNA ligase that effectively targets both DNA ligases I and III, with an IC50 of 10 μM for both enzymes. It specifically disrupts mitochondrial DNA metabolism in cancer cells. Inhibition of DNA ligase IIIα (LigIIIα) by L67 leads to significant alterations in mitochondrial morphology, reduces mitochondrial DNA levels, and increases reactive oxygen species (ROS) .

Alternative Products

CatalogName
CN-A038-500GMAgar, Micropropagation - Type I (Gracilaria)
M2302-20HPhaseShield™ Gel Tubes, Heavy (200x 2ml)
M2302-20LPhaseShield™ Gel Tubes, Light (200x 2ml)
BCS81BioCoupler® Glass Set (8 oz) x1
RHD55901Anti-PTGS1 Antibody (R1S27)
RHD55804Anti-TCEA1 Antibody (R1S24)
E-KAB-0614Porcine IL-2 Antibody Pair Set
RHD55803Anti-TCEA1 Antibody (R1S23)
PKSH030904Recombinant Human Purine nucleoside phosphorylase/PNP Protein (His Tag)
PKSH031350Recombinant Human Ficolin-1/Ficolin-A/FCN1 Protein (His Tag)

Popular Products